The Occurrence of Methicillin-Resistant <i>Staphylococcus Aureus</i> (MRSA) Around the World and Antibiotic Therapy for Selected Infections Caused By MRSA

Abstract Staphylococcus aureus is a Gram-positive bacterium, which can cause serious bacterial infections in humans. It constitutes an important etiological factor of many diseases, for instance, soft tissue and skin (including boils abscesses), as well life-threatening necrotizing pneumonia or toxic shock syndrome. estimated that about 25–30% people are carriers S. mainly the anterior nostrils. A smaller percentage methicillin-resistant (MRSA). In accordance with its definition, resistant to almost all β-lactam antibiotics. This phenomenon caused by presence penicillin-binding protein cell wall – PBP2a, product mecA gene, part complex called SCCmec (staphylococcal cassette chromosome mec ). Methicillin-resistant (MRSA) results endemic hospitals around world one leading causes morbidity mortality society. Infections initiated hospital strains MRSA (health care-associated MRSA, HA-MRSA) concern immunocompromised patients after surgery. addition, there populations acommunity-associated (CA-MRSA) livestock-associated (LA-MRSA) strains. The treatment etiology, exhausting possibilities standard antibiotic therapy use i.e. vancomycin, based on new-generation antibiotics, such dalbavacin.